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Loratadine; Pseudoephedrine

Loratadine, Pseudoephedrine Sulfate Oral tablet, extended release 12 hour

What is this medicine?

LORATADINE; PSEUDOEPHEDRINE (lor AT a deen; soo doe e FED rin) is a combination of an antihistamine and a decongestant. This medicine is used to treat the symptoms of allergies. It reduces congestion, sneezing, runny nose, and itching.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • diabetes

  • difficulty urinating

  • heart disease

  • high blood pressure

  • kidney disease

  • liver disease

  • thyroid disease

  • an unusual or allergic reaction to loratadine, pseudoephedrine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the label. You can take it with or without food. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be used in children as young as 12 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • bromocriptine

  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • medicines for allergies, colds, breathing difficulties

  • procarbazine

  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • digoxin

  • efavirenz

  • linezolid

  • medicines for depression like amitriptyline, nortriptyline

  • medicines for heart disease or blood pressure like atenolol, clonidine, doxazosin, mecamylamine, methyldopa, reserpine

  • St. John's wort

  • theophylline

  • tizanidine

  • yohimbine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better, if they get worse or if you have a high fever. If you have high blood pressure, check your blood pressure regularly. Ask your health care professional what your blood pressure should be, and when you should contact him or her.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash or hives, swelling of the face, lips, or tongue

  • breathing trouble

  • difficulty urinating

  • difficulty sleeping

  • dizzy, faint

  • fast, irregular heartbeat

  • high blood pressure

  • nervousness, agitation

  • tremor, muscle contractions

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough

  • dry mouth

  • headache

  • loss of appetite

  • nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.


Pseudoephedrine Sulfate, Loratadine Oral tablet, extended release 24 hour

What is this medicine?

LORATADINE; PSEUDOEPHEDRINE (lor AT a deen; soo doe e FED rin) is a combination of an antihistamine and a decongestant. This medicine is used to treat the symptoms of allergies. It reduces congestion, sneezing, runny nose, and itching.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • diabetes

  • difficulty urinating

  • heart disease

  • high blood pressure

  • kidney disease

  • liver disease

  • thyroid disease

  • an unusual or allergic reaction to loratadine, pseudoephedrine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the label. You can take it with or without food. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be used in children as young as 12 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • bromocriptine

  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • medicines for allergies, colds, breathing difficulties

  • procarbazine

  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • digoxin

  • efavirenz

  • linezolid

  • medicines for depression like amitriptyline, nortriptyline

  • medicines for heart disease or blood pressure like atenolol, clonidine, doxazosin, mecamylamine, methyldopa, reserpine

  • St. John's wort

  • theophylline

  • tizanidine

  • yohimbine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better, if they get worse or if you have a high fever. If you have high blood pressure, check your blood pressure regularly. Ask your health care professional what your blood pressure should be, and when you should contact him or her.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash or hives, swelling of the face, lips, or tongue

  • breathing trouble

  • difficulty urinating

  • difficulty sleeping

  • dizzy, faint

  • fast, irregular heartbeat

  • high blood pressure

  • nervousness, agitation

  • tremor, muscle contractions

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough

  • dry mouth

  • headache

  • loss of appetite

  • nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.


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