We continue to monitor COVID-19, flu and other respiratory viruses in our communities. Read the most current information about prevention, testing and where to go if you're sick.

COVID-19 Information
Select the search type
  • Site
  • Web
Go

Histidine

Other Name(s):

a-amino-b-[4-imidazole]-propionic acid

Claims

Histidine is an amino acid most people get from food. It's used in growth, repair of damaged tissues, and making blood cells. It helps protect nerve cells. It's used by the body to make histamine. Histidine supplements may help treat eczema.

Recommended intake

Amino acids (AAs) are available as single AAs or in AA combinations. They also come as part of multivitamins, proteins, and food supplements. The forms include tablets, fluids, and powders.

By eating enough protein in your diet, you get all of the amino acids you need.

There are no conditions that increase how much histidine you need.

Side effects and toxicity

Using a single amino acid supplement may lead to negative nitrogen balance. This can lessen how well your metabolism works. It can make your kidneys work harder. In children, single amino acid supplements may cause growth problems.

Single amino acid supplements aren’t advised for people who eat an adequate amount of protein. You shouldn't take high doses of single amino acids for long periods of time.

Taking too much histidine may cause psychological issues. It may also lead to mood disorders.

People who are pregnant or breastfeeding shouldn’t use histidine supplements.

2022 High Performance Badge - Kidney Failure

Find a doctor or make an appointment: 866.867.3627
General Information: 314.747.3000
One Barnes-Jewish Plaza
St. Louis, MO 63110
© Copyright 1997-2023, Barnes-Jewish Hospital. All Rights Reserved.