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Conditions Leading to Liver Transplant

If you or a loved one has end-stage liver disease (also known as chronic liver failure), and standard medical and surgical therapies no longer work, a liver transplant may be a lifesaving option. At the Washington University and Barnes-Jewish Transplant Center, our specialists provide comprehensive treatment plans and effective follow-up care to ensure the best possible outcomes for each patient.

Conditions Leading to Liver Transplant

Conditions that may lead to liver transplant include:

  • Acute liver failure: Rapid deterioration of the liver function, which can happen because of viruses or other infections, drug overdose or other toxins, cancer or autoimmune disease
  • Alpha-1-antitrypsin deficiency: A genetic disorder leading to abnormal amounts of A1AT protein in liver cells
  • Cholangiocarcinoma: Bile duct cancer, a rare cancer that is treated at only a few transplant centers, including the Washington University and Barnes-Jewish Transplant Center
  • Cirrhosis: A chronic degenerative disease of the liver that may result from alcoholism or hepatitis B or hepatitis C. Learn more about cirrhosis.
  • Hepatocellular carcinoma: Cancer that starts in the liver cells
  • Primary biliary cirrhosis (PBC): A slow deterioration of the bile ducts in the liver
  • Primary sclerosing cholangitis: Disease leading to scarring of the bile ducts
  • Wilson's disease: An inherited disorder that causes too much copper to accumulate in the liver, brain and other organs. Read more about Wilson’s disease.

Contact Us

For more information about the liver transplant program at the Washington University and Barnes-Jewish Transplant Center, call 888.994.2545.